Position Details
Position Information
| Recruitment/Posting Title |
Post-Doctoral Associate |
| Job Category |
Staff & Executive - Healthcare |
| Department |
RBHS |
| Overview |
New Jersey's academic health center, Rutgers Biomedical and Health Sciences (
RBHS) takes an integrated approach to educating students, providing clinical care, and conducting research, all with the goal of improving human health. Aligned with Rutgers University-New Brunswick and collaborating university wide,
RBHS includes eight schools, a behavioral health network, and five centers and institutes that focus on cancer treatment and research, neuroscience, advanced biotechnology and medicine, environmental and occupational health, and health care policy and aging research.
Our faculty are teachers, clinicians, and scientists with unparalleled experience who advance medical innovation and provide patient care informed by the latest research findings. We offer an outstanding education in medicine, dentistry, pharmacy, public health, nursing, biomedical research, and the full spectrum of allied health careers.
Our clinical and academic facilities are located throughout the state-at Rutgers University-New Brunswick, including Piscataway; and at locations in Newark, Scotch Plains, Somerset, Stratford, and other locations. Clinical partners include Robert Wood Johnson University Hospital in New Brunswick, Newark's University Hospital in Newark, and other affiliates.
Through this community of healers, scientists, and scholars, Rutgers is equipped as never before to transform lives. |
| Posting Summary |
Rutgers, The State University of New Jersey, is seeking a Post-Doctoral Associate in the Center for Advanced Biotechnology and Medicine (
CABM) of Rutgers Biomedical and Health Sciences (
RBHS).
Under the direction of the Principal Investigator, the Postdoctoral Associate will perform investigations on the molecular genetic basis of autism. The Postdoctoral Associate will investigate two independent lines of research. One, the molecular basis of macrocephaly, an autism endophenotype where the brain grows too big, too soon. iPSC-derived neural progenitor cells from macrocephalic autistic individuals will be analyzed using multi-omics and then manipulated molecularly to determine the molecular genetic pathways that contribute to macrocephaly. Two, to understand how cis-regulatory variants contribute to autism risk, enhancers will be identified in iPSC-derived neurons using multi-omics, cis-regulatory variants will be mapped onto these enhancers and then their function determined by Massively Parallel Reporter Assays (
MPRA). The research will involve stem cell, molecular and large omics data studies. In addition to experimental research and contributions to maintaining the laboratory, the Postdoctoral Associate will be expected to prepare manuscripts for publication, present research at local and national meetings, and contribute to grant applications and reporting. The Postdoctoral Associate will be expected to collaborate effectively with other members of the laboratory and will have an opportunity to guide undergraduate researchers.
Among the key duties of this position are the following:
- Performs experimental research on the molecular genetic basis of autism. Specifically, investigating the basis of the autism macrocephaly phenotype and how cis-regulatory variants contribute to autism risk.
- Uses stem cell, molecular genetic and omic techniques to understand the autism macrocephaly phenotype and how cis-regulatory variants contribute to disease risk.
- Performs: the culturing and maintenance of numerous iPSC lines, the generation and maintenance of NPCs from these iPSC lines, the generation and culturing of induced neurons from these iPSC lines, the isolation and analysis of RNA, protein and phospho-protein from these cultured cells, the molecular manipulation of these cells using knockdown, over-expression and viral transduction, the generation and handling of omic datasets, and the testing of cisregulatory variants using MPRA.
- Maintains detailed, organized and accessible records of experimental work including design, protocols, results, and conclusions.
- Designs, conducts, and interprets experiments with a high degree of independence. Contributes to developing new directions of investigations, informed by experimental results and knowledge of the field.
|
| FLSA |
Exempt |
| Grade |
|
| Salary Details |
A minimum of $63,968 for calendar year appointments |
| Minimum Salary |
20,000 |
| Mid Range Salary |
90,000 |
| Maximum Salary |
200,000 |
| Offer Information |
The final salary offer may be determined by several factors, including, but not limited to, the candidate's qualifications, experience, and expertise, and availability of department or grant funds to support the position. We also take into consideration market benchmarks, if and when appropriate, and internal equity to ensure fair compensation relative to the university's broader compensation structure. We are committed to offering competitive and flexible compensation packages to attract and retain top talent. |
| Benefits |
Rutgers provides a comprehensive benefits package to eligible employees. The specific benefits vary based on the position and may include:
- Medical, prescription drug, and dental coverage
- Paid vacation, holidays, and various leave programs
- Competitive retirement benefits, including defined contribution plans and voluntary tax-deferred savings options
- Employee and dependent educational benefits (when applicable)
- Life insurance coverage
- Employee discount programs
|
| Position Status |
Full Time |
| Working Hours |
|
| Standard Hours |
37.50 |
| Daily Work Shift |
Day |
| Work Arrangement |
his position requires a fully on-site work arrangement. |
| Union Description |
Post Docs - Regular Salaried |
| Payroll Designation |
PeopleSoft |
| Seniority Unit |
|
| Terms of Appointment |
Staff - 12 month |
| Position Pension Eligibility |
ABP |
Qualifications
| Minimum Education and Experience |
- PhD degree in Cell and Developmental Biology or a related scientific field is required.
- Candidates in All-But-Degree (ABD) status will also be considered but must hold a PhD degree by the start date of the appointment.
|
| Certifications/Licenses |
|
| Required Knowledge, Skills, and Abilities |
- Deep technical expertise in molecular genetics with a previous understanding of neurodevelopmental disorders as well as handling and analyzing omic datasets is required.
- Experience in human induced pluripotent stem cells, the generation of neural progenitor cells and induced neurons, the molecular manipulation of these cells using knock-downs, over-expression and viral transduction is required.
- Previous knowledge of Massively Parallel Reporter Assay (MPRA) workflow and manipulations are also a requirement.
|
| Preferred Qualifications |
- The ability to communicate effectively with the Principal Investigator and other laboratory members is essential.
- A commitment to conducting rigorous and reproducible research and documenting experimental results is essential.
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| Equipment Utilized |
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| Physical Demands and Work Environment |
PHYSICAL DEMANDS:
- Typical demands required for laboratory work, including: moving around a laboratory area, manual handling of reagents and small equipment such as pipettes, communicating with colleagues.
- Manual dexterity and vision sufficient for standard laboratory operations including pipetting, and use of instrumentation including microscopes.
WORK ENVIRONMENT;
- Laboratory environment.
- Low to moderate noise. Universal safety precautions are mandatory.
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| Special Conditions |
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Posting Details
| Posting Number |
26ST0364 |
| Posting Open Date |
|
| Special Instructions to Applicants |
|
| Regional Campus |
Rutgers Biomedical and Health Sciences (RBHS) |
| Home Location Campus |
Piscataway (RBHS) |
| City |
Piscataway |
| State |
NJ |
| Location Details |
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Pre-employment Screenings
All offers of employment are contingent upon successful completion of all pre-employment screenings.
Immunization Requirements
Under Policy 100.3.1 Immunization Policy for Covered Individuals, if employment will commence during Flu Season, Rutgers University may require certain prospective employees to provide proof that they are vaccinated against Seasonal Influenza for the current Flu Season, unless the University has granted the individual a medical or religious exemption. Additional infection control and safety policies may apply. Prospective employees should speak with their hiring manager to determine which policies apply to the role or position for which they are applying. Failure to provide proof of vaccination for any required vaccines or obtain a medical or religious exemption from the University will result in rescission of a candidate's offer of employment or disciplinary action up to and including termination.
Equal Employment Opportunity Statement
It is university policy to provide equal employment opportunity to all its employees and applicants for employment regardless of their race, creed, color, national origin, age, ancestry, nationality, marital or domestic partnership or civil union status, sex, pregnancy, gender identity or expression, disability status, liability for military service, protected veteran status, affectional or sexual orientation, atypical cellular or blood trait, genetic information (including the refusal to submit to genetic testing), or any other category protected by law. As an institution, we encourage all qualified applicants to apply. For additional information please see the Non-Discrimination Statement at the following web address: http://uhr.rutgers.edu/non-discrimination-statement
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